{"id":393,"date":"2022-11-03T16:19:32","date_gmt":"2022-11-03T08:19:32","guid":{"rendered":"https:\/\/damakey.com\/?p=393"},"modified":"2023-05-24T15:10:43","modified_gmt":"2023-05-24T07:10:43","slug":"%e8%99%95%e6%96%b9%e7%ae%8b","status":"publish","type":"post","link":"https:\/\/damakey.com\/?p=393","title":{"rendered":"\u8655\u65b9\u7b8b"},"content":{"rendered":"

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\u300e<\/span>……<\/span>\u8a31\u591a\u71df\u990a\u88dc\u5145\u54c1\u542b\u6709\u7684\u7dad\u751f\u7d20\u6216\u7926\u7269\u8cea\u8d85\u904e\u6bcf\u65e5\u7684\u63a8\u85a6\u5291\u91cf\uff0c\u800c\u4e14\u6211\u5011\u901a\u5e38\u4e0d\u7f3a\u9019\u4e9b\u3002\u7dad\u751f\u7d20<\/span>E<\/span>\u7684\u88dc\u5145\uff0c\u88ab\u8a8d\u70ba\u8207\u7e3d\u6b7b\u4ea1\u7387\u589e\u52a0\u6709\u95dc\u3002\u651d\u53d6\u7684\u7dad\u751f\u7d20<\/span>A<\/span>\u53ea\u8981\u9054\u5230\u6bcf\u65e5\u63a8\u85a6\u5291\u91cf\u7684\u5e7e\u500d\uff0c\u5c31\u53ef\u80fd\u5c0e\u81f4\u795e\u7d93\u7cfb\u7d71\u3001\u809d\u81df\u3001\u9aa8\u9abc\u3001\u76ae\u819a\u7684\u75be\u75c5\uff0c\u5728\u61f7\u5b55\u671f\u9593\u5247\u53ef\u80fd\u9020\u6210\u80ce\u5152\u5148\u5929\u7f3a\u9677\u3002\u9ad8\u5291\u91cf\u7dad\u751f\u7d20<\/span>C<\/span>\u6703\u9020\u6210\u8179\u7009\u548c\u814e\u7d50\u77f3\u3002\u904e\u91cf\u7684\u92c5\u6703\u5c0e\u81f4\u9435\u548c\u9285\u7684\u5438\u6536\u4e0d\u8db3\u3002\u7dad\u751f\u7d20<\/span>D<\/span>\u904e\u91cf\u5247\u6703\u9020\u6210\u8840\u9223\u904e\u9ad8\u3002<\/span>β-<\/span>\u80e1\u863f\u8461\u7d20\u6703\u589e\u52a0\u80ba\u764c\u7684\u98a8\u96aa\u3002\u9435\u6703\u9020\u6210\u56b4\u91cd\u7684\u6bd2\u6027\uff0c\u7dad\u751f\u7d20<\/span>B6<\/span>\u6703\u5f15\u8d77\u795e\u7d93\u50b7\u5bb3\u3002\u5291\u91cf\u904e\u9ad8\u7684\u9240\u6703\u9020\u6210\u5fc3\u8df3\u505c\u6b62\u3002<\/span>……<\/span>\u300f<\/span>*<\/span><\/p>\n

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\u300e<\/span>……<\/span>\u5728\u5305\u62ec\u6fb3\u6d32\u7684\u5927\u90e8\u5206\u570b\u5bb6\u88e1\uff0c\u516c\u885b\u7d44\u7e54\u5df2\u4e0d\u518d\u5efa\u8b70\u70ba\u7121\u75c7\u72c0\u8005\u9032\u884c\u5927\u898f\u6a21\u7be9\u6aa2<\/span>……<\/span>\uff0c\u56e0\u70ba\u9019\u7a2e\u6aa2\u67e5\u4e00\u518d\u88ab\u8b49\u5be6\uff0c\u5c0d\u5065\u5eb7\u8005\u9020\u6210\u7684\u50b7\u5bb3\u9060\u5927\u65bc\u5c0d\u300c\u5f97\u75c5\u8005\u300d\u7684\u52a9\u76ca\u3002<\/span>……<\/span>\u6bcf\u4e00\u5343\u4eba\u63a5\u53d7\u6aa2\u9a57\u5341\u5e74\uff0c\u53ef\u4ee5\u9810\u9632\u5169\u4eba\u6b7b\u65bc\u651d\u8b77\u817a\u764c\u3001\u9810\u9632\u5169\u500b\u4eba\u5f97\u5230\u8513\u5ef6\u5168\u8eab\u7684\u764c\u75c7\u3001\u5c0e\u81f4\u516b\u5341\u4e03\u500b\u4eba\u56e0\u70ba\u507d\u967d\u6027\u800c\u505a\u5207\u7247\u3001\u5c0e\u81f4\u4e8c\u5341\u516b\u500b\u4eba\u88ab\u8a3a\u65b7\u51fa\u7f79\u60a3\u7d42\u8eab\u4e0d\u6703\u9020\u6210\u50b7\u5bb3\u7684\u764c\u75c7\u3001\u4ee4\u4e8c\u5341\u4e94\u500b\u4eba\u4e0d\u5fc5\u8981\u5730\u5c07\u651d\u8b77\u817a\u5207\u9664\u6216\u505a\u653e\u7642\u3002\u300f<\/span>*<\/span><\/p>\n

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\u300e<\/span>……<\/span>\u8981\u6551\u56de\u4e00\u500b\u751f\u547d<\/span>(<\/span>\u63a5\u53d7\u7be9\u6aa2\u5973\u6027\u4eba\u6578\u7684\u5343\u5206\u4e4b\u4e00<\/span>)<\/span>\uff0c\u5c31\u8981\u6709\u4e03\u5341\u5230\u4e00\u767e\u4f4d\u63a5\u53d7\u7be9\u6aa2\u7684\u5973\u6027\u9032\u884c\u4e0d\u5fc5\u8981\u7684\u5207\u7247\u3001\u4e09\u5230\u5341\u56db\u4f4d\u5973\u6027\u63a5\u53d7\u4e0d\u5fc5\u8981\u7684\u624b\u8853\u3001\u653e\u5c04\u7dda\u6216\u5316\u5b78\u6cbb\u7642\u3002<\/span>…..<\/span>\u300f<\/span>*<\/span><\/p>\n

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\u6240\u4ee5\uff0c\u745e\u58eb\u91ab\u5b78\u6703\u5df2\u7d93\u5728<\/span>2014<\/span>\u5e74\u5efa\u8b70\uff0c\u505c\u6b62\u745e\u58eb\u7684\u4e73\u764c\u7be9\u6aa2\u8a08\u5283\u3002<\/span><\/p>\n

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\u300e<\/span>……<\/span>\u7279\u5b9a\u85e5\u7269\u672c\u8eab\u4e26\u4e0d\u6703\u300c\u81f4\u766e\u300d\u6216\u8a98\u767c\u6feb\u7528\uff0c\u800c\u662f\u500b\u4eba\u7684\u904e\u5f80\u6b77\u53f2\u3001\u5fc3\u7406\u72c0\u614b\u3001\u907a\u50b3\u9ad4\u8cea\u50be\u5411\u53ca\u793e\u6703\u8655\u5883\uff0c\u5c0e\u81f4\u4e86\u7269\u8cc7<\/span>(<\/span>\u6309\uff1a\u6307\u85e5\u7269\u6216\u9152\u7cbe\u7b49<\/span>)<\/span>\u6feb\u7528\u3002\u4ee5\u9152\u7cbe\u70ba\u4f8b\uff0c<\/span>……<\/span>\u67d0\u4e9b\u4eba\u665a\u9910\u6703\u559d\u4e00\u676f\u8461\u8404\u9152\uff0c<\/span>……<\/span>\u6709\u4eba\u6bcf\u9031\u559d\u4e00\u6b21\u3001\u6bcf\u6708\u559d\u4e00\u6b21\u3001\u6216\u53ea\u5728\u8056\u8a95\u7bc0\u559d\uff0c\u6216\u8005\u5728\u661f\u671f\u65e5\u671b\u5f4c\u6492\u6642\u559d\u5230\u9152\u3002\u6709\u4eba\u6bcf\u5929\u4e0b\u5348\u4e00\u9ede\u6703\u9023\u7e8c\u559d\u6389\u5169\u74f6\u7136\u5f8c\u9189\u5012\uff0c\u56e0\u70ba\u96e3\u4ee5\u5fcd\u53d7\u6f2b\u9577\u53c8\u7a7a\u6d1e\u7684\u4e0b\u5348\u3002\u4e5f\u6709\u4eba\u5f9e\u65e9\u4e0a\u9192\u4f86\u559d\u5230\u665a\u4e0a\u9589\u773c\u3002\u4e0a\u8ff0\u4f7f\u7528\u9152\u7cbe\u7684\u65b9\u5f0f\uff0c\u90fd\u6709\u4e0d\u540c\u7684\u610f\u7fa9\u3001\u6c88\u6fb1\u7269\u3001\u5f71\u97ff\uff0c\u4ee5\u53ca\u6109\u6085\u5230\u50b7\u5bb3\u7684\u6bd4\u4f8b\u3002\u7981\u4ee4\u4e26\u4e0d\u6703\u5e6b\u52a9\u90a3\u4e9b\u6feb\u7528\u9152\u7cbe\u7684\u4eba\uff0c\u4f46\u662f\u793e\u6703\u652f\u6301\u8207\u5fc3\u7406\u5065\u5eb7\u652f\u6301\u537b\u53ef\u4ee5\u3002\u5176\u4ed6\u6240\u6709\u5a1b\u6a02\u85e5\u54c1\u4e5f\u5b8c\u5168\u4e00\u6a23\uff0c\u5f9e\u6d77\u6d1b\u56e0\u5230\u5927\u9ebb\u90fd\u662f\u3002\u300f<\/span>*<\/span><\/p>\n

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\u300e<\/span>……<\/span>\u6578\u4ee5\u5343\u8a08\u7684\u75c5\u4eba\u5728\u624b\u8853\u5f8c\u6309\u7167\u91ab\u56d1\u670d\u7528\u9ad8\u5291\u91cf\u9d09\u7247\u5291\u5e7e\u9031\uff0c\u7b49\u5230\u9aa8\u982d\u6216\u53d7\u50b7\u7684\u5167\u81df\u7652\u5408\u5c31\u76f4\u63a5\u505c\u85e5\u3002<\/span>……<\/span>\u6d3e\u99d0\u8d8a\u5357\u7684\u7f8e\u8ecd\u4e2d\uff0c<\/span>20%<\/span>\u5728\u884c\u65c5\u4e2d\u662f\u91cd\u5ea6\u9d09\u7247\u8005\uff0c\u9019\u4e9b\u4eba\u6709<\/span>95%<\/span>\u5728\u8fd4\u62b5\u5bb6\u9115\u5f8c\u5c31\u5b8c\u5168\u505c\u7528\u4e86\u3002<\/span>……<\/span>\u91cd\u8981\u7684\u662f\u5730\u9ede\u3001\u65b9\u5f0f\u3001\u539f\u56e0\u548c\u4eba\uff0c\u800c\u4e0d\u5728\u65bc\u300c\u6771\u897f\u300d\uff1b\u95dc\u9375\u662f\u4f86\u9f8d\u53bb\u8108\u7684\u80cc\u666f\uff0c\u800c\u4e0d\u662f\u7269\u8cea\u3002<\/span>…….<\/span>\u300f<\/span>*<\/span><\/p>\n

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\u5728<\/span>1970<\/span>\u5e74\u4ee3\uff0c\u52a0\u62ff\u5927\u5fc3\u7406\u5b78\u5bb6\u5e03\u9b6f\u65af·\u4e9e\u529b\u5c71\u5927<\/span>(Bruce K. Alexander)<\/span>\uff0c\u6bd4\u8f03\u4e86\u4e0d\u540c\u751f\u6d3b\u74b0\u5883\u5c0d\u8001\u9f20\u55dc\u98df\u55ce\u5561\u7684\u5dee\u5225\u3002\u4e00\u7d44\u662f\u5708\u990a\u5728\u7a7a\u7c60\u5b50\u4e2d\uff0c\u53e6\u5916\u4e00\u7d44\u5247\u5728\u6709\u8f49\u8f2a\u3001\u73a9\u5177\u5bdb\u655e\u7684\u7a7a\u9593\u88cf\u3002\u7d50\u679c\u524d\u8005\u6bd4\u5f8c\u8005\u98df\u7528\u7684\u55ce\u5561\u591a\u51fa<\/span>19<\/span>\u500d\u4e4b\u591a\u3002<\/span><\/p>\n

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<\/span><\/p>\n

\u300e<\/span>……<\/span>\u6709\u4e9b\u4eba\u66fe\u627f\u53d7\u96e3\u4ee5\u60f3\u50cf\u7684\u5275\u50b7\u3002\u6211\u5e38\u5750\u5728\u75c5\u4eba\u9762\u524d\u8046\u807d\u4ed6\u5011\u7684\u5f80\u4e8b\uff0c\u89ba\u5f97\u4ed6\u5011\u80fd\u5b58\u6d3b\u4e0b\u4f86\u771f\u662f\u4e0d\u53ef\u601d\u8b70\uff0c\u5f88\u60f3\u77e5\u9053\u4ed6\u5011\u6bcf\u5929\u65e9\u4e0a\u8981\u600e\u9ebc\u8d77\u5e8a\u3001\u7a7f\u8863\uff0c\u8b93\u81ea\u5df1\u8d70\u51fa\u5bb6\u9580\u3002\u66fe\u7d93\u5728\u751f\u547d\u4e2d\u906d\u9022\u9019\u7a2e\u75db\u82e6\u7684\u4eba\uff0c\u7269\u8cea\u6feb\u7528<\/span>(<\/span>\u5408\u6cd5\u6216\u975e\u6cd5<\/span>)<\/span>\u7684\u98a8\u96aa\u6703\u9ad8\u51fa\u8a31\u591a\uff0c\u5fc3\u7406\u5065\u5eb7\u75be\u60a3\u7684\u98a8\u96aa\u4e5f\u662f\uff0c\u50cf\u662f\u5275\u50b7\u5f8c\u58d3\u529b\u75c7\u3001\u6182\u9b31\u75c7\u53ca\u7126\u616e\u75c7\u3002<\/span>…….<\/span>\u300f<\/span>*<\/span><\/p>\n

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\u9019\u4e5f\u662f\u70ba\u4ec0\u9ebc\u85e5\u7269\u4e0a\u766e\u7684\u4eba\uff0c\u90fd\u96c6\u4e2d\u5728\u751f\u6d3b\u6bd4\u8f03\u8ca7\u7aae\u7684\uff0c\u5c6c\u65bc\u793e\u6703\u7d93\u6fdf\u5e95\u5c64\u7684\u4eba\u3002\u5982\u679c\u6211\u5011\u6709\u4e00\u500b\u6eab\u6696\u7684\u539f\u751f\u5bb6\u5ead\uff0c\u57fa\u672c\u4e0a\u6bd4\u8f03\u4e0d\u6703\u6709\u85e5\u7269\u4e0a\u766e\u7684\u554f\u984c\u3002\u6211\u5011\u5c31\u50cf\u662f\u6d3b\u5728\u6709\u8f49\u8f2a\u6709\u73a9\u5177\u6709\u5bb6\u5ead\u6eab\u6696\u652f\u6301\u7684\u5c0f\u8001\u9f20\u4e00\u6a23\uff0c\u6211\u5011\u6709\u5f88\u591a\u6bd4\u55ce\u5561\u9084\u66f4\u6709\u5438\u5f15\u529b\u7684\u5feb\u6a02\u4f86\u6e90\uff0c\u4f55\u5fc5\u7368\u937e\u55ce\u5561\u5462\uff1f<\/span><\/p>\n

<\/span><\/p>\n

\u5c0d\u65bc\u85e5\u7269\u4e0a\u766e\u7684\u4eba\uff0c\u6700\u6070\u7576\u7684\u505a\u6cd5\uff0c\u4e26\u4e0d\u662f\u76f4\u63a5\u7981\u7528\u85e5\u7269\u3002\u300e<\/span>…..<\/span>\u9019\u5df2\u7d93\u6709\u5be6\u4f8b\u8b49\u660e\u4e86\uff1a\u53ea\u8981\u75c5\u4eba\u88ab\u958b\u7acb\u6d77\u6d1b\u56e0\u6216\u5b89\u975e\u4ed6\u547d\u70ba\u8655\u65b9\uff0c\u540c\u6642\u4e5f\u5f97\u5230\u5fc3\u7406\u5065\u5eb7\u3001\u4f4f\u5c4b\u53ca\u5de5\u4f5c\u6a5f\u6703\u7b49\u652f\u6301\u3002\u4ed6\u5011\u6c92\u6b7b\uff0c\u72af\u7f6a\u4e8b\u4ef6\u6e1b\u5c11\uff0c\u4ed6\u5011\u6709\u5de5\u4f5c\u53ef\u505a\uff0c\u4ed6\u5011\u7684\u5b69\u5b50\u56de\u5bb6\u4e86\u3002\u300f<\/span>*<\/span><\/p>\n

<\/span><\/p>\n

\u9019\u4e9b\u662f\u6fb3\u6d32\u91ab\u5e2b\u51f1\u502b·\u5e0c\u5340\u8003\u514b\u7684\u89c0\u5bdf\uff0c\u4f46\u5979\u767c\u73fe\u8981\u958b\u7acb\u7981\u7528\u85e5\u7269\u7684\u8655\u65b9\u7b8b\uff0c\u5728\u4fdd\u5b88\u7684\u6fb3\u6d32\u662f\u56f0\u96e3\u91cd\u91cd\u3002<\/span><\/p>\n

<\/span><\/p>\n

\u6211\u67e5\u4e86\u4e00\u4e0b\u53f0\u7063\u7684\u505a\u6cd5\uff0c\u885e\u670d\u90e8\u5728<\/span>2006<\/span>\u5e74\u5c31\u9812\u4f48\u4e86\u300a\u9d09\u7247\u985e\u7269\u8cea\u6210\u766e\u66ff\u4ee3\u6cbb\u7642\u4f5c\u696d\u57fa\u6e96\u300b\uff0c\u63a5\u8457\u5728\u540c\u5e74\u53ca<\/span>2011<\/span>\u5e74\u6709\u4fee\u5b9a\uff0c\u91dd\u5c0d\u6212\u65b7\u7121\u6548\u8005\uff0c\u5f97\u5728\u672c\u4eba\u66f8\u9762\u540c\u610f\u4e4b\u4e0b\uff0c\u7531\u91ab\u5e2b\u958b\u7acb\u8655\u65b9\u7b8b\uff0c\u6cbb\u7642\u4ee5\u66ff\u4ee3\u85e5\u7269\u7f8e\u6c99\u51ac\u9e7d\u9178\u9e7d<\/span>(Methadone HCL)<\/span>\u548c\u4e01\u57fa\u539f\u5561\u56e0\u9e7d\u9178\u9e7d<\/span>(Buprenorphine HCL) <\/span>\u70ba\u4e3b\uff0c\u5176\u4e2d\u524d\u8005\u5fc5\u9808\u5728\u91ab\u4e8b\u4eba\u54e1\u76e3\u7763\u4e0b\u670d\u4e0b\uff0c\u5f8c\u8005\u5247\u53ef\u9650\u91cf\u56de\u75c5\u60a3\u64d5\u56de\u81ea\u884c\u670d\u7528\u3002<\/span><\/p>\n

<\/span><\/p>\n

\u5176\u5be6\u5927\u5bb6\u90fd\u77e5\u9053\uff0c\u8eab\u5fc3\u8981\u5065\u5eb7\uff0c\u4e0d\u5916\u662f\u98f2\u98df\u5747\u8861\u3001\u9069\u7576\u904b\u52d5\u3001\u5145\u8db3\u7761\u7720\u3001\u4e0d\u8981\u9577\u671f\u627f\u53d7\u58d3\u529b\u7b49\u7b49\u3002\u5728\u8cc7\u672c\u4e3b\u7fa9\u7d93\u6fdf\u4e4b\u4e0b\uff0c\u6211\u5011\u53d7\u5230\u5ee3\u544a\u7684\u8a98\u60d1\uff0c\u5403\u4e86\u592a\u591a\u7684\u52a0\u5de5\u98df\u54c1\u3001\u5783\u573e\u98df\u7269\uff0c\u5403\u4e86\u592a\u591a\u7684\u7cd6\uff0c\u5403\u592a\u591a\u3001\u5403\u592a\u98fd\uff0c\u8b8a\u5f97\u592a\u80d6\u53c8\u6709\u4e09\u9ad8\u3002\u5de5\u4f5c\u6216\u6253\u96fb\u73a9\u71ac\u591c\u525d\u596a\u4e86\u6211\u5011\u7684\u7761\u7720\uff0c\u9084\u6709\u4eba\u969b\u95dc\u4fc2\u4e0a\u7684\u5404\u7a2e\u58d3\u529b\uff0c\u600e\u9ebc\u80fd\u5920\u904e\u5065\u5eb7\u7684\u751f\u6d3b\u5462\uff1f<\/span><\/p>\n

<\/span><\/p>\n

\u6709\u4eba\u5b9a\u7fa9\u5e78\u798f\u662f\uff1a\u5403\u5f97\u4e0b\u53bb\uff0c\u62c9\u5f97\u51fa\u4f86\uff0c\u7761\u5f97\u8457\u89ba\uff1b\u4e5f\u5c31\u662f\u5403\u559d\u62c9\u6492\u7761\u3002\u9084\u771f\u662f\u6709\u9053\u7406\u554a\uff01<\/span><\/p>\n

<\/span><\/p>\n

*<\/span>\uff1a\u300a\u8655\u65b9\u7b8b\u300b\uff0c\u51f1\u502b·\u5e0c\u5340\u8003\u514b<\/span> <\/span>\u8457\uff0c\u5289\u601d\u6f54<\/span> <\/span>\u8b6f<\/span><\/p>\n

<\/span><\/p>\n

2022\/11\/3 <\/span>\u8655\u65b9\u7b8b<\/span> Damakey<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

\u6211\u5011\u5e73\u5e38\u53ea\u8981\u98f2\u98df\u5747\u8861\uff0c\u539f\u5247\u4e0a\u4e0d\u9700\u8981\u53e6\u5916\u88dc\u5145\u7dad\u751f\u7d20\u3002 \u300e&he…<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"content-type":"","footnotes":""},"categories":[3],"tags":[],"class_list":["post-393","post","type-post","status-publish","format-standard","hentry","category-3"],"_links":{"self":[{"href":"https:\/\/damakey.com\/index.php?rest_route=\/wp\/v2\/posts\/393","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/damakey.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/damakey.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/damakey.com\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/damakey.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=393"}],"version-history":[{"count":1,"href":"https:\/\/damakey.com\/index.php?rest_route=\/wp\/v2\/posts\/393\/revisions"}],"predecessor-version":[{"id":19332,"href":"https:\/\/damakey.com\/index.php?rest_route=\/wp\/v2\/posts\/393\/revisions\/19332"}],"wp:attachment":[{"href":"https:\/\/damakey.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=393"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/damakey.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=393"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/damakey.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=393"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}